Better understanding of the risk of developing dementia

when people at the same time Type 2 diabetes and heart disease Bear, doubled This you risk of developing dementia, Preventing diabetes and heart disease can also help reduce the risk of dementia.

In a new study by experts Karolinska Institute In Sweden, the combined effect of cardiometabolic diseases on the risk of developing dementia was investigated. The results were published in the journal “Alzheimer’s and Dementia” free.

Data from 2,500 participants were evaluated

for new research Data from the Swedish National Study on Aging and Care Used. Overall, data from 2,500 Healthy people over the age of 60 who did not suffer from dementia at the start of the study.

At the start of the study, the incidence of cardiometabolic diseases was evaluated Medical records and clinical examinations laid down. participant then. were for the duration of Medical supervision for twelve years,

In addition, participants had to take cognitive tests so that changes in cognitive abilities And this development of dementia Observed according to experts.

How does dementia develop?

Dementia develops very slowly and takes decades. The disease first manifests itself gradual cognitive declinewhich can only be determined in cognitive tests.

Poor memory as a sign of dementia

According to the team, the next step is a cognitive impairment to which the affected persons themselves notice that they are subject to poor memory are suffering but still able to take care of themselves. Eventually, full-blown dementia develops and the patient can no longer independently cope with everyday life.

Cardiometabolic disease risk factors for dementia

so called cardiometabolic disease (type 2 diabetes, ischemic heart disease, congestive heart failure, atrial fibrillation and stroke) Most important risk factors for dementiaResearchers report.

So far “Few studies have examined how the coexistence of several of these diseases affects the risk of dementia, and that’s exactly what we wanted to investigate in our study.‘ explains the study authors abigail dove one in Press release,

Double risk of dementia identified

Analysis of the data revealed that the presence of more than one cardiometabolic disease rate of cognitive decline remarkably quick, It also raised the risk of dementia doubling, the researchers report.

that Risk increases with number of diseases start and specific combination of diseases seemed to increase the risk of dementia particularly strongly. ,In our study, the combination diabetes/heart disease and diabetes/heart disease/stroke were most detrimental to cognitive function‘ Pigeon reports.

Experts say that, however, people who only a cardiometabolic disease was, No higher risk of dementia Exhibited.

It may prevent dementia from developing

,that’s good news. Study suggests risk increases only if someone has at least two of these diseases“, emphasizes dove, It is therefore possible to prevent dementia by preventing the development of another disease.

Prevention already in middle age

The study also found that the association between cardiometabolic disease and dementia risk was stronger in participants younger than 78.

,We should therefore focus on preventing cardiometabolic disease from middle age, as the risk of cognitive failure and dementia appears to be higher in people who develop cardiometabolic disease earlier in life.“, like that dove,

In the future, the team hopes to learn more about the mechanisms underlying this association. this is what the effect should be genetic factors examined and brain imaging is used to determine how Cardiometabolic diseases damage the brain capable. (as)