Arthritis: The “hormone of happiness” may help in healing

rheumatoid Arthritis The most common is rheumatic-inflammatory joint disease, The disease leads to the destruction of cartilage and adjacent bones. The role of messenger matter has been researched for years dopamine in the development and progression of the disease. It is now reported that the so-called “happiness hormone“The bone metabolism Can affect gout.

Dopamine, the so-called “happiness hormone,” controls many processes in the brain that are associated with the control of movements, emotions, and motivation. In addition, dopamine indirectly affects the human defense system, explains the Leibniz Institute for Labor Research at TU Dortmund (IFADO). Website, And it may affect bone metabolism in arthritis, according to a paper published in the journal “CellsPublished study shows.

Dopamine’s role in bone metabolism

There are several treatments today that can significantly reduce the effects of rheumatoid arthritis (RA). Bone loss and bone loss (osteoporosis) is still a problem, as of the present message Of Ifado.

majority of Osteoporosis Treatment While aimed at preventing bone loss, some treatments are able to actively promote the formation of new bone tissue to restore the bone structure that has already been lost.

Building on previous studies, researchers Ifado examined the role of the neurotransmitter dopamine in the bone metabolism of RA patients in more detail.

Scientists come to the conclusion that controlling dopamine is needed for new therapeutic approaches. bone loss Can be used in rheumatoid arthritis.

dopamine receptors found in bone tissue

Group Prof. In a current project, Dr. Sylvia Capellino researched the importance of the biochemical messenger dopamine for the bone-building process in rheumatoid arthritis. dopamine is a neurotransmitters The central nervous system, which controls movement, emotions, and cognition.

Dopamine receptors, the receiving unit for signals from neurotransmitters, im. Were bone tissue found it.

presence of dopamine receptors finding in RA patients that dopamine also plays a role in the physiology of human bone metabolism.

Therefore, the researchers provide hypothesis showed that the dopamine-activated signaling pathway in inflamed joints also affects bone metabolism in rheumatoid arthritis.

This led the experts to conclude that the decoding of these dopamine-controlled signaling pathways in bone metabolism paved the way for new therapeutic approach To control bone loss. (advertisement)