The patient is a 70-year-old man with the so-called MALT lymphoma, a type of cancer that affects the mucous membrane. Due to the disease and its treatment, he suffered from an immune deficiency. He was also infected with Sars-CoV-2. Researchers believe that a weakened immune system has led to the chronic course of Kovid-19.

Mutation treatment abolished

The man was treated with Remedivir twice – but without success. Two serum treatments with convulsive plasma also did not prevent infection. She later received remediesvir and serum therapy. After 102 days, Kovid-19 finally died. The virus’s genome was sequenced 23 times during this period.

It was discovered that the virus had changed several times during treatment: according to the team, the most severe development had occurred after serum treatments. Antibodies in plasma were only able to eradicate some viruses present in the body, but treatment with mutated viruses does not seem to be appropriate.